Manhattan Melodrama
- Sal: 1934
- Welat: United States of America
- Genre: Crime, Drama, Romance
- Studio: Cosmopolitan Productions, Metro-Goldwyn-Mayer
- Keyword: friendship, woman between two men, organized crime, orphan, pre-code, best friends on opposite sides
- Serek: W.S. Van Dyke
- Avdan: Clark Gable, William Powell, Myrna Loy, Leo Carrillo, Nat Pendleton, George Sidney